12^th International Conference on Pediatric, Perinatal and Diagnostic Pathology July 13-14, 2018 Toronto, Ontario, Canada

Biography:

Abstract:

The asymptomatic phase of type 1 diabetes is recognised by the presence of beta cell autoantibodies in the absence of hyperglycaemia. We propose that an accurate description of this stage is provided by the name ‘Autoimmune Beta Cell Disorder’ (ABCD). Specifically, we suggest that this nomenclature and diagnosis will, in a proactive manner, shift the paradigm towards type 1 diabetes being first and foremost an immune-mediated disease and only later a metabolic disease, presaging more active therapeutic intervention in the asymptomatic stage of disease, before end-stage beta cell failure. Furthermore, we argue that accepting ABCD as a diagnosis will be critical in order to accelerate pharmaceutical, academic and public activities leading to clinical trials that could reverse beta cell autoimmunity and halt progression to symptomatic insulin-requiring type 1 diabetes. We recognize that there are both opportunities and challenges in the implementation of the ABCD concept but hope that the notion of ‘asymptomatic autoimmune disease’ as a disorder will be widely discussed and eventually accepted.

Biography:

SIMONE BATTIBUGLI relocated to Dubai 4 years ago.Currently working as Pediatric Orthopedic Surgeon at The Children’s Medical Centre in Dubai.10 years clinical and research experience as faculty of Federal University of Sao Paulo.

 Pediatric Orthopedic training:

• Pediatric Orthopedic Fellowship at Feinberg School of Medicine at Northwestern University. Children's Hospital. Chicago, IL, USA.
• Pediatric Orthopedic Fellowship at Shriners Hospital for Children. Lexington, KY, USA.

 Main Interests:

• Evidence based Medicine Systematic
• Literature Review    
• Management and clinical research on neuromuscular disorders; as Cerebral Palsy, Spina Bifida and Arthrogryposis Multiplex Congenita. 
•  Congenital foot and lower limb deformities and other congenital and acquired musculoskeletal pathologies in children. 

Abstract:

Cerebral palsy is the result of a non-progressive lesion or injury to developing brain and has multiple causes and clinical manifestations, making a discussion on diagnosis and screening challenging. In the past, the diagnosis of cerebral palsy was largely a clinical diagnosis, with the development of imaging it has been recommended that clinical diagnosis of cerebral palsy should be confirmed by imaging.

Early diagnosis is challenging, however is extremely important as it provides opportunity early intervention. Recently, there is a renewed interest in the newborn qualitative assessment of general movements. This cost effective diagnostic tool consists of observing the infant’s spontaneous movements with promising results providing high specificity and sensitivity.

Poor control of muscles and movement in children with cerebral palsy can be associated with a wide range of functional challenges. Traditional efforts to manage these motor disabilities have been directed at improving tone and promoting adequate motor patterns.  Contemporary approaches to treatment are addressing muscle weakness as a common element of functional problems with encouraging results.

Brain and muscle plasticity in response to specific types of therapy has been demonstrated in CP. The amazing developmental changes of the brain between preterm age and the age of 1 year post-term offer opportunities for early intervention. The goal of motor training is to optimize the development of skilled motor function. Fixed contractures are managed by lengthening of the muscle–tendon unit by the technique that delivers the safest and most effective surgical technique that will give appropriate amount of lengthening of the muscle for the child in question.

Given that cerebral palsy presents at early in infancy and persists throughout an individual’s lifetime, the disorder needs to be thought of and managed in the context of development, functioning with a family based and community integration. 

Biography:

Abstract:

The first incidence of phenylketonuria in Ankara in 1983 with a pilot study to investigate the screening program began in Turkey, has been expanded upon determination that high. Diseases such as phenylketonuria, congenital hypothyroidism, cystic fibrosis and biotinase deficiency can be detected with the Heel Blood Test, which is a simple and inexpensive method with a few drops of blood in the next 5-10 days after birth. Jaundice is the most common problem in the newborn and should be carefully monitored with the reason for the toxic effects of bilirubin. Hypothyroidism, one of the causes of indirect hyperbilirubinemia, is one of the most important endocrine diseases of childhood. Congenital hypothyroidism Symptoms and signs are very rare during the neonatal period. It is very important to detect congenital hypothyroidism in the early period and to eliminate the cause of the effect of thyroid hormone on the child's motormental development.

Biography:

Working as a sugeon in MO Civil Hospital Rohtak, India 

Abstract:

INTRODUCTION

Neonatal sepsis remains a diagnostic burden globally responsible for about 30-50% of the total neonatal deaths each year in developing countries. Neutrophil CD64 is found to be a promising marker for diagnosis of early and late infections in newborns. Decreased expression of HLA-DR on monocytes has been associated with decreased survival in newborn with sepsis. The purpose of this study is to evaluate the role of neutrophil CD64 and monocyte HLA-DR expression in diagnosis and prognosis of neonatal sepsis.

MATERIALS AND METHODS

This was a prospective study carried out in Department of Pathology in collaboration with Neonatal services division, Department of Paediatrics, Pt.B.D.Sharma Post Graduate Institute of Medical Sciences, Rohtak. Seventy full term  neonates with clinical suspicion of sepsis and warranting antibiotic therapy were enrolled provided they had not received antibiotics in the preceding 72 hours after an informed parental consent. Thirty age matched healthy neonates were taken as controls. The peripheral venous blood sample was collected for flow cytometry, blood culture and sepsis screening in all patients. Cell surface markers (CD64 on neutrophils and HLA-DR on monocytes) expression was measured by 8 Color Flow cytometer BD FACS Canto II (Becton Dickinson, San Jose,CA) system. A composite parameter was derived by division of MFI (mean fluorescence intensity) values of nCD64 and their respective mHLA-DR and multiplying the ratio by 100, and termed as sepsis index (Sepsis Index= nCD64/mHLA-DR x 100).

 RESULTS

Out of the 70 neonates studied nineteen cases were diagnosed as definite sepsis (culture positive), 27 as probable sepsis (sepsis screen positive but culture negative) and 24 as no sepsis. nCD64 positivity was seen in all cases of definite sepsis and 88.89% cases of probable sepsis. mHLA DR was positive in 63.16% cases of definite sepsis, 85.19% in probable sepsis and 54.17% of no sepsis group. Out of 19 cases of definite sepsis 94.74% cases had positive sepsis index while one case had sepsis index less than cutoff value. In our study, nCD64 revealed 100% sensitivity, 87.5% specificity, 86.36% positive predictive value, 100 % negative predictive value and 93.02% of diagnostic accuracy in culture positive sepsis. However; downregulation of mHLA-DR observed in our study alone showed a poor diagnostic utility. In definite sepsis group mHLA DR revealed sensitivity of 63.15%, specificity of 45.83%, PPV of 48%, NPV of 61.11% and accuracy of 53.48%. Sepsis index was calculated in all the neonates in this study and found sensitivity of 94.73%, specificity of 62.50%, PPV of 66.66% and NPV of 93.75% and accuracy of 76.74% in definite sepsis group

Biography:

ISLAM FAHED Nablus, West Bank, Palestine

Current job: specialist of Pediatric & Neonatal Surgery in Rafedia hospital, Nablus, Palestine

Dedicated neonatal and pediatric surgeon specializing in treating and operating neonatal children. Pediatric Surgeon with experience performing surgeries on both emergency and elective cases. Extensive knowledge of anesthesia, complex lacerations, surgery, trauma resuscitation andadvanced cardiac life support.

SKILLS:

• Conducted hundreds of major and minor pediatric and neonatal operations independently
• Medical research comprehension
• Dedicated to integrity
• Strong interpersonal skills
• Open-minded communicative surgeon
• Compassionate professional
• Pediatric critical care medicine
• Culturally sensitive
• Good clinical judgment

Abstract:

The objective of this study was to find out the diagnostic accuracy Doppler ultrasound in diagnosis of testicular torsion children presenting with scrotal pain taking surgical findings as Gold Standard.  In this diagnostic cross sectional study we took 120 male patients of 1-14 years of age with acute scrotal pain (12-48 hours) and with clinical suspicion of testicular torsion. Doppler ultrasonography was carried out in all the patients by a single radiologist. All patients were sent for surgery and intraoperative findings were noted. All surgeries were done by a single surgical team. All this information was recorded on proforma (attached). Statistical analysis was performed by entering all the data in SPSS version 20.

In this study the mean age of patients was 9 ± 2.52 years. The mean duration of scrotal pain 16.12 ±5.03 and average scrotal pain on visual analogue scale (VAS) was 7.17 ± 1.50.  The Sensitivity, Specificity, Positive predictive value and negative predictive value of Doppler ultrasonography was 98.21%, 87.5%, 99.1%, 77.78% respectively. The overall diagnostic accuracy was 97.5%. 

According to this study, Doppler ultrasonography can be used to detect testicular torsion in patients presenting with acute scrotal pain with reliable sensitivity (98.21%), specificity (87.5%) and good diagnostic accuracy (97.5%). 

Biography:

Dr. Joeidith Natalí Véliz Osteicoechea, born on July 6, 1978, in the Cardón community, Carirubana municipality, Falcón state, Venezuela. He studied Diversified Education in Punto Fijo, Falcon state, in the U.E. College "San Francisco Javier", where he obtained the title of Bachiller in Sciences, being first in its promotion. He studied higher education, at the National University Experimental "Francisco de Miranda" (UNEFM), obtaining the title of Medical Surgeon, in the city of Coro, Falcon state; Placing itself of Third position in the Promotion. His Postgraduate Residency of Traumatology and Orthopedics was held at the Hospital Universitario de Coro "Dr. Alfredo Van - Grieken ", since December 2007, December 2010 graduating with the title of Specialist in Traumatology and Orthopedics, obtaining recognition as first place in his class. She holds Internships in Child Orthopedics, at the Caracas-Venezuela Children's Orthopedic Hospital, as part of the post-graduate training in Traumatology and Orthopedics for 6 months, and where she finds her interest in this area. He worked as a Rural Physician and Coordinator in the rural outpatient type II "Luis Felipe Ruiz Castillo", in Urumaco, Falcón state, from August 2004 to February 2006. He performs Residency of Traumatology and Orthopedics at the Hospital Universitario de Coro "Dr. Alfredo Van - Grieken ", from February of 2006 to December of 2007. He was Chief of Residents of Postgraduate of Traumatology and Orthopedics of the Hospital Universitario de Coro" Dr. Alfredo Van - Grieken ". In the Orthopedic Children's Hospital of Caracas - Venezuela, an internationally recognized institution, he undertook the specialization in Orthopedics for the period 2013-2014, obtaining recognition for his high academic dedication. He is currently Assistant I in the Traumatology and Orthopedics Service of IVSS Hospital Cardón "Dr. Juvenal Bracho "since June 2015 and has been head of this service since June 2017. He has belonged to the staff of Specialists in Orthopedics at Cardón Medical Center and Polyclinic Paraguaná since January 2015. He has received several Honors of Merit awards for his effort and academic dedication .

His main area of research interest is the Child Orthopedics presenting works in different congresses as Klisic Technique in Hip Development Dysplasia. About a case. Post Axial Hypoplasia of M.I. Severe Distal Defect. Correction of Equine Foot valgus and Tibial Deformity. Curved Juvenile Back. Management of the Parallel Valve Flat Foot by the Technique of Medial Osteoarthritis (Astragalus - Escafoidea). Tumor of Giant Cells in the Thoracic Spine. About a case.

Abstract:

Deformities in the feet are common occurrence in children with Cerebral Infantile Paralysis, can produce multiple functional deficits. Among these deformities stands out after the flat foot, Hallux Valgus (HV), which causes a painful foot, which is not plantigrade or stable, leading to a loss of the pre-requisites of walking for those wandering patients, and impossibility of use of orthesis for both ambulatory and for those with potential for standing and walking. HV is a component of the ankle-foot malalineation complex that is often present in children with cerebral palsy, this deformity is acquired during the years of growth, as a result of the intrinsic and extrinsic muscle imbalance. In this research was raised to compare the surgical management of the deformity of hallux valgus paralytic by the technique of fusion technical vs. Kramer Bösch in patients with PCI, review the group age, gender and type of motor dysfunction, radiological characteristics pre-operative and post operative, identify complications associated with the procedure. This study is of type documentary, retrospective, descriptive, observational, analytical level of cohort, correlation and evaluation. You were evaluated 31 patients (49 feet ) met the inclusion criteria. There was clearly satisfactory results for both techniques; still the technique of percutaneous distal osteotomy of the first metatarsal with Kramer-Bosch technique most used in the clinic of NeurOrthopedic

Keywords: hallux valgus, cerebral palsy child, Arthrodesis, osteotomy, Kramer.

Biography:

Mercede Enshaei has completed her Pediatric Specialty at the age of 32 years from Gilan University of Medical Sciences. She studied Genetic Counseling at Tehran University of Medical Sciences, and she will begin the Pediatric Hematology and Oncology Subspecialty from September 2018. 

Abstract:

Movement disorders are a growing field of pediatric neurology. Unlike adults, it seems children are more likely to suffer from hyperkinetic movement disorders. Some studies have been done on serum iron in affected adults, but there are limited data in pediatrics. This survey case-control study was aimed to compare iron profiles in children with hyperkinetic movement disorders with healthy children.

We evaluated 50 children 2-12 years of age with hyperkinetic movement disorders including 18 tic disorders, ten dystonia, 8 chorea, 6 myoclonus, 3 stereotypies, 3 athetosis (with a history of neonatal kernicterus) and 2 tremor; 26 male and 24 female with mean age of 8.2±2.37 (2-12) years.  Fifty healthy children as age and sex-matched controls were enrolled too. In children with hyperkinetic movement disorders serum iron, TIBC, and serum ferritin were 51.8 ± 2.77µg/dl, 450± 9.42 µg/dl and 47.92 ± 7.87 ng/ml; while in normal children these amounts were 81.4±3.94 µg/dl, 356 ± 12.34 µg/dl and 140.68 ± 13.61 ng/ml respectively. The differences of each parameter between two groups were statistically significant. (P-value < 0.05)

There was a significant difference between patients with hyperkinetic movement disorders and healthy controls regarding iron profiles. Our findings suggest that decreased blood iron levels may have a predisposing effect on hyperkinetic movement disorders, although the knowledge about the mechanism is still limited. Since these disorders affect the quality of life, it seems further studies are needed to understand the mechanism and make some recommendations on prevention or control of the disease.

Biography:

FATIHA BENNAOUI is an Assistant Professor of Pediatrics, graduate in Neonatal-Perinatal Medicine from Medecine School ; Cadi Ayad University ; Marrakesh, and health services researcher in the section of General Pediatrics. She leads the faculty and post-doctoral fellows in Neonatology, in Newborn Intensive Care Units at University Hospital ; Marrakesh. In addition, she is actively involved in the perinatl education of Yale medical students, attending physicians, fellows, residents, nurses, and physician associate students, she has for many years served as medical faculty. She has more than 5 years of experience as a clinical neonatologist and over 10 years of experience in pediatric medicine.

Dr. BENNAOUI has been an invited lecturer nationally and internationally, focusing on analyse of pediatric medicine. She has many publications ; more than 12 papers indexed in scopus and in pubmed. She has served on the Moroccan Association of Pediatrics.

Abstract:

Introduction: Prematurity is a common condition. It is responsible in Morocco for a morbidity and neonatal mortality rate.

Objective: The objective of the study is to assess the conditions of women who give birth prematurely

Materials and methods: All preterm infants hospitalized during the year 2016 were included in this study. The analysis of the files identified the different parameters’ mothers.

Results: The rate of admission of premature babies to the service is 19%. The most common maternal age was between 18 and 35 years of age (80%). 68% of women are multiparous, and more than 40% of women have a history of miscarriage. Pregnancy was not followed in 27% of cases, antenatal corticosteroids were administered in 45% of cases, pregnancy was multiple in 25%, premature rupture of membranes was noted in 36% of cases, and maternal infection was 33%. Birthing was predominant with a rate of 73%. The majority of premature babies admitted to the service (64%) come from birth delivered at the university hospital center.  Non-induced prematurity accounts for the majority of cases with 78% of cases. The overall prematurity mortality rate is 62% among all preterm infants

Conclusion: Prevention would reduce the rate of prematurity and improve its management, especially through close obstetric-pediatric collaboration.

Biography:

FATIHA BENNAOUI is an Assistant Professor of Pediatrics, graduate in Neonatal-Perinatal Medicine from Medecine School ; Cadi Ayad University ; Marrakesh, and health services researcher in the section of General Pediatrics. She leads the faculty and post-doctoral fellows in Neonatology, in Newborn Intensive Care Units at University Hospital ; Marrakesh. In addition, she is actively involved in the perinatl education of Yale medical students, attending physicians, fellows, residents, nurses, and physician associate students, she has for many years served as medical faculty. She has more than 5 years of experience as a clinical neonatologist and over 10 years of experience in pediatric medicine.

Dr. BENNAOUI has been an invited lecturer nationally and internationally, focusing on analyse of pediatric medicine. She has many publications ; more than 12 papers indexed in scopus and in pubmed. She has served on the Moroccan Association of Pediatrics.

Abstract:

Blood culture provides an undeniable ideal aid in the diagnosis of neonate infection, its result is reliable. The aim of our study was to evaluate the bacteriological profile of bacteremia, admitted newborns from maternity hospital IBN TOFAIL.

Retrospective study on the cases of newborns hospitalized in the neonatal intensive care, University hospital Mohamed VI,Marrakesh, originating from the delivery room of the gynecology-obstetric department IBN TOFAIL, over a period of 6 months, June to November 2016.Of the 125 blood cultures collected, 43 were positive, representing an over all positivity rate of 34.4%. Positive staphylococcal coagulase negative hemocultures were 27. Other bacteremias were 16, consisting essentially of multiresistant germs with the predominance of Klebsiella pneumoniae (5 cases), followed by Acinetobacter Baumanii (4 cases) and Serratia marcescens in 3 cases.

The bacteremia on admission ; especially to multiresistant germs presents a major problem of therapeutic management.We emphasize the necessity to improve the conditions of delivery in our context and to develop new diagnostic and therapeutic strategies.

Biography:

Dr Sura Al-Rawabdeh a senior specialist in Pediatric pathology working in the royal medical services in Jordan.She got  fellowship training in pediatric pathology. In nationwide children’s hospital Columbus Ohio USA 

Abstract:

The patient is an 11-year-old boy who presented with a 1-day history of abdominal pain and emesis but no fever. His past medical history was unremarkable. In particular, there was no history of hemorrhagic problems or systemic disease. The family history was also unremarkable. On physical examina- tion, he had persistent and well-localized right lower quad- rant and right flank tenderness at the expected location of his appendix (McBurney’s point). The laboratory findings were unremarkable. WBC was 4.9 K/microliter with the following differentials: 49% segmented neutrophils, 41% lymphocytes, 9% monocytes, and 1% eosinophils. There was no evidence of anemia or thrombocytopenia (hemoglobin = 13 g/dL, hematocrit = 36%, and platelet count = 291 K/microliter). A computed tomography scan (CT-Scan) of the abdomen showed an enlarged appendix without inflammation; how- ever, ultrasound images showed a fluid-filled appendix with a diameter within the upper rages of normal. A subsequent physical examination revealed an increase in abdominal pain and tenderness, and, consequently, the patient underwent a laparoscopic appendectomy.

Gross evaluation showed a pink-tan appendix, measuring 8.3 cm in length and 1 cm in diameter. The serosal surface was unremarkable and cut surface demonstrated no fecalith. Microscopically, hematoxylin-eosin-stained sections of the tip of the appendix revealed numerous lipid-laden xanthoma cells in the mucosa which were surrounded by lymphocytes and plasma cells admixed with multiple mult- inucleated giant cells containing cholesterol clefts.The rest of the mucosa showed patchy mild neutrophilic infiltration.

The postoperative clinical course was unremarkable. The patient was discharged home the following day and had an unremarkable physical examination on a follow-up visit three weeks later

Biography:

Dr. Sushil Dhungel completed his  MBBS, MS. And now working in Department of Surgery, Annapurna Children and Women’s Hospital, Pokhara, Nepal.

Abstract:

OBJECTIVE: 

The aim of this study was to compare the three different treatment methods and investigate the effectiveness of the therapeutic effect of common salt on umbilical granuloma.

METHODS: 

This retrospective study involved patients who were treated in our clinic for umbilical discharge disease between December 2015 and December 2016. The patients were divided to three subgroups according to treatment methods. Group I: Cases treated with only local common salt on umbilical granuloma, group II: cases treated with silver nitrate, group 3: cases treated with electro cauterization under intravenous anesthesia.

RESULTS: 

In this study, 75 patients with the diagnosis of umbilical discharge were treated in our clinic. The patients were classified into three groups; group I included 28 patients, group II included 25 patients and group III included 22 patients. During 6-12 months of follow-up, no recurrences occurred in all 3 groups. The overall cure rate was 100%. No complication was observed during treatment. Healing time and resolution rates were identical for silver nitrate and common salt. Mild side effects were occasionally reported, all of which were self-limiting.

Biography:

Abstract:

Background: Varicocele is generally considered the most common correctable cause of male infertility. Testicular disproportion is considered to be the most important sign of testicular damage in absence of the possibility to do routine semen analysis in adolescent.

Aim: The aim of our work is to evaluate feasibility, recurrence rate and postoperative complications of laparoscopic varicocelectomy with preservation of the testicular artery in adolescents.

Patient and methods: Our prospective clinical study was done between May 2016 and May 2017 at pediatric surgery unit, General Surgery Department, Tanta University Hospital. The study included twenty patients presented with symptomatic varicocele. Then, laparoscopic varicocelectomy with preservation of the testicular artery were done for all cases. Operation time, the success rate, the incidence of complications, the length of the hospital stay, conversion and data of follow up were recorded.

Results : Total Operation time ranged between 10 and 40 minutes. There were testicular catch up growth in 5 cases and we had no testicular atrophy in the other cases Recurrence occurred in 2 cases in the period of follow up (6 months).

Biography:

Mr. Vahid Karami, MSc in medical physics at Dezful University of Medical Sciences, Dezful, Iran. I have 30 years old. My field of interest is radiation protection in diagnostic radiology and especially on pediatric imaging. I have 29 scientific papers in the field, 13 conference paper and one registered invention. 

Abstract:

Abstract

Background and Objective: Computed tomography (CT) is one of the powerful diagnostic tools that frequently request by physicians to address of the variety of clinical problems in patients. Medical applications and the radiation exposure associated with CT have continued to increase, especially in the two past decades. In 2011, 85 million CTs were conducted in the United States, up from about 3 million in 1980. Although patients can undoubtedly benefit from these procedures, their use involves some potential health risks. The radiation dose associated with most CT procedures is as much as 100 to 500 times more than those from conventional radiography and is in the range of levels known to increase the lifetime risk for developing cancer. The aim of this study was to addresses the cancer risk associated with CT. 

Biography:

Elham Rayzan is a last year medical student in “Tehran University of Medical Sciences” (TUMS). She has started her research activities in “Universal Scientific Education and Research Network” (USERN) as a junior researcher.

She is the managing director of “International Hematology/Oncology of Pediatrics’ Experts” (IHOPE) group since 2016. IHOPE is one of USERN’s interest groups that has started working with junior scientists and is focused on state of the art researches in the mentioned field.

Elham is planning to continue her education in Pediatrics’ Hematology/Oncology and she is thinking of find a cure for hematologic malignancies.

Abstract:

Statement of the Problem:

One of the most harmful DNA damages is double-strand break which results from genotoxic stress. NHEJ1/ Cernunnnos/ XLF protein is a DNA repair factor that plays an important role in non-homologous end-joining pathway. Recent studies revealed that mutations in this gene can cause different types of severe combined immunodeficiency disorders.This report describes clinical and laboratory features of a girl with dysregulation in antibody production due to homozygous NHEJ1 mutation.

Methodology & Theoretical Orientation:

In this report, we are going to present a nineteen months-old Iranian girl who was referred to “Children’s Medical Center” with a history of high fever and hemolytic anemia. Her parents were first cousins and there was no positive family history of diseases.

The very early symptoms of the disease were started at the age of eleven months-old with high fevers and two episodes of coombs positive hemolytic anemia. Since no specific infection site was found and the fevers did not respond to usual treatments, more investigation was performed. The Immunoglobulin test showed a remarkable rise in serum IgM level, while serum IgG level was decreased.

Diagnosis of “Hyper IgM” was made just after retesting the levels of serum immunoglobulins. Nevertheless, the second test was performed after a single dose IVIG injection, determined high levels of serum IgM although the IgG level was increased. In order to comprehend the genetic pattern of the disease, whole exome sequencing was done. The results showed homozygous NHEJ1 mutation in the patient’s genome. 

Biography:

Madineh Hassani  has completed his MA at the age of 25 years from Tehran University of Medical Sciences,she has been Graduated from Shahid Beheshti University of medical sciences, as Bachelor, with the specialties including Occupational Therapist (Rehabilitation and then started working at The Tabriz University of medical sciences as lecturer where she has continued his research. Presently he has been working at the at the Paveh City in Ocuupational Therapy Clinic

Abstract:

Objective: Since the according to International Classification of Functioning, Disability and Health (ICF) participation is the ultimate outcome for individuals with disabling conditions, Children with cerebral palsy are at risk of reduced participation in everyday activities, Purpose of this study is review of Life habits according ICF in children with Cerebral palsy.

Materials & methods: In this cross sectional study 53children with cerebral palsy (5-13 years old) from rehabilitation centers were selected via the non-probability convenience sampling. The quality of accomplishment of life habits and the overall satisfaction with performance were assessed via Life-H Questionnaire through interviews with parents. Life habits divided into 12 categories. The categories nutrition, fitness, personal care, communication, housing and mobility refer to daily activities; the categories responsibilities, interpersonal relationships, community life, education employment and recreation address social roles.

Biography:

I am Yasir Alrashdan, 23 years old , 5^th year medical student at Hail University, medical college. I have done some research with Dr. M. Parvaiz Farshori who has many important researches at medical filed.This is my 2^nd personal research and I hope to present it at your conference.

Abstract:

Hyponatremia manifests most commonly with neurologic dysfunction and results more from the rate of change of sodium concentration. This review discusses the recent evidence concerning the pathophysiology, risk factors and treatment techniques. We performed detailed search through electronic databases; PubMed, and EMBASE, for studies published in English language and human subjects thought instant to 2017. Studies discussing the acute hyponatremia in pediatrics, management approaches. Hyponatremia is a severe adverse event that can be avoided with proper
IV fluids option and cautious monitoring. Because hospitalized children are at an increase danger for hyponatremia secondary to nonosmotic stimulus that could stimulate the release of ADH, isotonic intravenous (IV) fluids appears to be a safer empirical option. The studies discussed demonstrate that the use of isotonic IV fluids could decrease the risk of hospital-acquired hyponatremia. There is proof to sustain that hypotonic saline solutions could trigger acute hyponatremia, which may result in severe unfavorable effects and even fatality, especially in postoperative patients. Like all drugs, there is no ideal IV fluids for all kids, so response to IV fluids therapy need to be observed closely. When hypotonic saline is utilized health care providers need to be educated on the signs and symptoms associated with acute hyponatremia.

Biography:

Dr Hiba A. Awooda is an Assistant Professor at the department of physiology, faculty of medicine. She successfully completed her master and Ph.D in the feild of neuropphysiology from Alexandria University (2011) and Al Neelain University (2013) respectively. As well as master of medical education from University of Khartoum. She teaches physiology to undergraduate medical, dental, physiotherapy and nurse students. She is also a researcher with interest in developing biomarkers that are used in the treatment of acute ischemic stroke. She has published more than 20 papers in reputed journals

Abstract:

Role of nitric oxide (NO) inhibition in cerebral ischemia/reperfusion (I/R) remains uncertain; this work aimed to explore the neuroprotective potential of N-Nitro-L-Arginine-Methylester (L-NAME) non-selective NO synthase (NOS) inhibitors.The study involved 30 adult male Wistar rats (150-250g), divided into three groups;10 rats in each: sham-operated group (control), I/R group: infused with 0.9% normal saline intraperitoneally prior to 30 minutes of left common carotid artery occlusion followed by 24-hour of reperfusion, third group (test group): infused with L-NAME (15 mg/kg per weight) intraperitoneally 15 minutes prior to the same I/R period. Neurobehavioral assessments were evaluated using six clinical tests. Proper anesthesia was induced. Western blotting was used to estimate Nuclear factor kappa B (NF-Ò›B), Tumor necrosis factor-α (TNF-α) using ELISA and NO metabolites (nitrite and nitrate), were measured colorimetrically in both plasma and affected cerebral hemisphere. Result shows that L-NAME group demonstrates a significant improvement in neurological deficit (P <0.001) compared to both I/R and control groups. In I/R rats NF-Ò›B was significantly increased compared to the control group and L-NAME pretreatment resulted in a significant decrease in NF-Ò›B (P <0.001) compared to I/R group. Serum level of TNF-α and NO were significantly increased in I/R group compared to the control group (P <0.001), while L-NAME administration resulted in a significant decrease in serum TNF-α and NO (P <0.001) compared to the I/R group. In conclusions L-NAME pretreatment for rats undergoing cerebral ischemia/reperfusion significantly improve neurological deficit through it is anti-inflammatory effect in a rat’s model of transient focal cerebral ischemia reperfusion.

Biography:

Marjan  Entezami  has completed her medical doctorate at the age of 25 years  from Islamic Azad University Tehran Faculty of Medicine, Iran. She is working as a general practitioner in the emergency department of Tafresh  Hospital , Arak ,Iran .Her thesis about “comparison of the therapeutic effects of UVB and  PUVA therapy in patients with vitiligo” was published in online Skin and Beauty Magazine in 2017.

Abstract:

Abstract:

Background : Vitiligo is a common pigmentary  disorder with great cosmetic and psychological morbidities . Although many  treatment modalities have been tried for the treatment of vitiligo , none is uniformly effective. PUVA (Psoralen Ultra Violet A) is established as efficacious treatment for vitiligo. Recently, narrow band UVB(NBUVB) has been reported to be an effective and safe therapeutic  option in patients with vitiligo. In this study, patients with vitiligo  divided into two groups that   were treated either with UVB or PUVA therapy modalities and the efficacy ,the time required for repigmentation, stability of repigmentation and adverse effects were compered in two groups.

Methods: A clinical trial has been performed on 60 patients with vitiligo referred to BOUALI hospital  and MEHREGAN laser center in 1392 and  treated with UVB and PUVA therapy methods.

In first group that were  treated with PUVA (30 patients), oral   tablets containing 8-methoxypsoralen at a dose of 25 mg/ m² were taken 3 hours  before  phototherapy and PUVA therapy was started at a dose of 0.5 J/cm² twice a week. The phototherapy dose was increased by 20%  in each visit  if tolerated.

In second group( 30 patients) , UVB therapy was administered twice a week  with 311-313 nm wavelength and a dose of 0.1 J/cm² and we increased the dose 20% in each visit if tolerated .phototherapy sessions in both groups were  15. In patients treated with PUVA , 40% were male (12 patients) and 60% were female(18 patients).In UVB group 43.3% were male (13 patients) and 56.7% were female(17 patients).The mean age in PUVA- treated group is 34 years and in UVB- treated group is 32.1 years. There was no statistically significant difference on comparing mean age in both groups.(p=0.13). Type of vitiligo in patients treated with PUVA was 56.7% generalized, 30% segmental and 13.3 % focal ,and in patients treated with UVB was 56.7 % generalized,33.3% segmental and 10% focal.

Biography:

Abstract:

Abstract

Background: The growth of children is a health indicator at each country and growth monitoring has a great importance. This study was done to determine the anthropometric indices of secondary school students of Hamadan, west of Iran.

Methods: This was a cross-sectional study. 816 girl & boy secondary school students in Hamadan selected based on cluster random multistage sampling. We gathered data through questionnaire. The status of anthropometric indices was assessed by height, weight and body mass index and then it was compared with the NCHS standards. The analysis of data was done through statistic tests (Regression and T-test) by using SPSS/16.